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Published: 28/05/25

Brain Potential: The Cutting-Edge Neuro-Health Program to Prevent Cognitive Decline

Based on a multidisciplinary scientific approach, this advanced method combines precision diagnostics, genetics, advanced imaging, and neurotechnologies to enhance cognitive functions and counteract brain aging. – By Veronica Grimaldi | 24 May 2025

This article originally appeared in Vanity Fair Italia and has been translated and adapted for publication on the Clinique La Prairie website. The original article can be found here.

Brain Potential is considered one of the most advanced methods globally for brain health. Currently available in Switzerland and China, it merges precision diagnostics, genetics, advanced imaging, and neurotechnologies to enhance cognitive functions and combat brain aging. Dr. Adrian Heini, Medical Director at Clinique La Prairie in Montreux, provides detailed insights into how it works.

Dr. Heini, the Brain Potential program is regarded as one of the best worldwide. What does it entail?

“Brain Potential was developed through a collaboration between Clinique La Prairie's Longevity Innovation department in Montreux and the Centre for Research in Neurosciences LREN (CHUV) in Switzerland. It's the result of a two-year research project culminating in a publication in the prestigious journal Neuroscience and Biobehavioral Reviews. The program is built upon an innovative scientific model of brain health. Each journey begins with the Longevity Master Assessment (LMA), the most advanced preventive analysis system globally. This cutting-edge tool provides a 360-degree view of the patient's health and aging status by analyzing over 300 biological markers through both standard and complex screenings.

In addition to the panels included in the LMA, the Brain Potential program integrates specific tests focused on brain health, enabling the medical and healthcare team to apply a highly precise care model. These sophisticated longevity indicators also allow for the mapping of personalized health trajectories, with a particular focus on brain function, offering patients effective and tailored interventions over time.”

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What technologies are employed?

“Our approach to neuro-health integrates precision medicine with a solid medical foundation and cutting-edge diagnostic technologies. Among the tools used are innovative molecular screenings (such as epigenetic stress tests and microbiota DNA analyses) and advanced brain imaging techniques. The program includes specific exams like brain MRI with AI software capable of quantifying different brain areas, as well as cardiovascular tests crucial for assessing major risk factors affecting brain health.

A distinctive aspect of the program is the attention dedicated to cardiovascular and neuromuscular health, both key elements in the brain aging process. Through comprehensive cardiological evaluations and movement analyses supported by state-of-the-art technologies, a personalized path is designed to specifically address the individual's cognitive needs. Some tests, like Senaptec, include specific exercises to improve weaker cognitive areas, such as three-dimensional perception.

From the very beginning of the journey, targeted supplements and nutritional guidelines are prescribed to enhance brain capacity. The main focus remains neuroplasticity, the brain's ability to adapt and regenerate, while simultaneously addressing the primary factors that determine its decline.”

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How does the program integrate genetic analyses into personalized plans for each participant?

“It's now well-known that genetic predisposition is one of the factors that can favor the decline of cognitive abilities. However, the goal of the genetic tests used in the program is not to diagnose the risk of diseases like Alzheimer's but rather to identify improvable elements—such as the impact of stress—through a precision medicine approach.

Genetic profiling focuses on 'actionable' genes, meaning those genetic variants on which it's possible to intervene to optimize brain and cognitive health. The proprietary genetic panel includes the analysis of predisposition to chronic inflammation (closely linked to neuroinflammation), omega-3 fatty acid metabolism (essential for brain health and powerful anti-inflammatories), and B-vitamin metabolism, crucial for cognitive function. Genetic markers related to sleep quality and efficiency, memory, oxidative stress risk—which is harmful to neurons—as well as individual metabolism of substances like caffeine and alcohol, both relevant factors in brain aging, are also examined.”

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Are there variations in the protocols that particularly consider risk differences between sexes, for example, in the predisposition to neurodegenerative diseases like Alzheimer's?

“The Brain Potential program does not vary based on gender. Hormonal differences between men and women do not influence the application or effectiveness of the protocol, thanks to the high level of personalization guaranteed in each journey.”

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What is the proven effectiveness of the AudioVitality® technology, which involves brain stimulation and stress management?

“Although still relatively new, AudioVitality® technology is already showing promising results in terms of improving concentration and brain relaxation. This patented technology is an integral part of the Brain Potential program and is based on low-frequency vibrational therapies to promote neuro-relaxation and enhance mental well-being.

Among the protocols available at Clinique La Prairie are: a non-medical relaxation protocol integrated into wellness journeys; a protocol dedicated to sleep disorders (currently undergoing internal testing); and a medical protocol for tinnitus, recognized and reimbursed by Swiss insurance companies. The program also includes other non-invasive technologies such as cardiac coherence therapy and sessions against sleep apnea, for a synergistic and lasting effect on overall well-being.”

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How is the correlation between gut well-being and cognitive function scientifically evaluated within the program?

“The gut and brain constantly communicate through a system known as the gut-brain axis, a complex bidirectional network connecting the gastrointestinal tract, microbiota, and central nervous system. This connection is the foundation of the program's neuro-nutritional approach.

The clinic employs next-generation sequencing (NGS) technologies to deeply analyze the patient's gut microflora and develops highly precise probiotic protocols formulated based on individual results. The result is a targeted intervention that directly supports cognitive functions and combats neuroinflammation and brain decline.”

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Are there follow-up protocols or post-program maintenance strategies to ensure lasting benefits for participants?

“At the end of the stay, each participant receives a complete maintenance kit to continue the benefits achieved. This includes a personalized dietary plan, specific supplements for brain longevity (BP Longevity Kit), a weekly cognitive training program via the Clinique La Prairie app, breathing exercises to improve sleep and relaxation, a tailored monthly probiotic regimen, and access to AudioVitality sessions through the app. A set of strategies designed to ensure continuity and lasting improvement in brain health.”

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For now, the program is exclusively available at Clinique La Prairie in Montreux, Switzerland, and at the Health Resort in Anji, China. What long-term results have been observed in participants who have followed the Brain Potential program?

“Since it was launched less than a year ago, it's still early to draw definitive conclusions about the program's long-term results. However, the initial feedback received from participants is positive and promising.”

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How does the Brain Potential program differ from other solutions on the market?

“It stands out significantly due to its robust scientific foundation and exemplary medical team. It's probably the only program in the world that involves neurologists, psychologists, and psychiatrists in a multidimensional approach to brain health. It includes highly sophisticated screenings such as brain MRI with volumetric analysis and the Longevity Master Assessment. These are complemented by an exclusive nutraceutical protocol with supplements specifically developed for neuroprotection and cognitive enhancement.”

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How are the neuroactive enhancement formulas and cellular nutrigenomic supplements personalized for each participant?

“During the program, the Neuronutrition protocol is applied: a nutritional approach with high anti-inflammatory potential aimed at supporting neurotransmitter synthesis. In parallel, participants receive the Brain Potential Longevity Kit, a range of exclusive supplements developed internally to promote neuroprotection and improve cognitive functions. These supplements are administered only during the stay at the clinic as an integral part of the brain health protocol.”

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Your Wellbeing Index Assessment evaluates the link between mental health and longevity. How does it work?

“It's a tool designed to analyze the key aspects of mental health that influence longevity. Through a detailed scoring system, the WIA provides a holistic assessment of factors such as sleep, stress, mood, fatigue, social connection, and happiness. Based on the results, a comprehensive report is compiled with indications on strengths and areas for improvement. The personalized therapeutic path—which may include low-frequency vibrations, cryotherapy, transcendental meditation, guided breathing, and relaxation protocols—is developed by a wellness therapist in synergy with the referring doctor and psychologist.”

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For more information, you can read the original article on Vanity Fair Italia's website: https://www.vanityfair.it/gallery/brain-potential-il-programma-di-neuro-salute-avanguardia-prevenire-il-decadimento-cerebrale-ecco-come-funziona.

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